Mushroom Empire

Glycerosome Extraction Technology

Glycerosome technology is Mushroom Empire's proprietary extraction method that encapsulates bioactive compounds in chitosan-stabilized glycerol-based vesicles, delivering 5-10x enhanced bioavailability compared to standard extracts.

Developed in partnership with Dr. Bartosz Zambron (Institute of Physical Chemistry, Polish Academy of Sciences) and Croda Pharma. Published research validates superior absorption for cognitive health applications.

The Problem

Low bioavailability of crucial compounds like terpenes (hericenones, erinacines) in standard mushroom extracts. Poor absorption due to molecular structure and degradation in the GI tract means supplements often fail to deliver on their promises.

Our Solution

Proprietary chitosan-stabilized glycerosomes with enhanced penetration and controlled release. Nano-sized vesicles with positive charge actively adhere to cell membranes, protecting compounds through GI transit and dramatically improving cellular uptake.

The Result

Radically enhanced absorption ensuring your products deliver on their promises with measurable efficacy. 5-10x bioavailability improvement validated by published research and third-party laboratory analysis.

How It Works: 4-Step Manufacturing Process

Each step is optimized for maximum encapsulation efficiency and bioactive compound preservation.

1

Water-Alcohol Extraction

Captures the full spectrum of bioactive compounds including water-soluble polysaccharides (beta-glucans) and alcohol-soluble terpenes (hericenones, erinacines, ganoderic acids, triterpenes).

Dual-solvent system ensures no bioactive compound is left behind.

2

High-Pressure Homogenization

Creates nano-sized glycerosome vesicles enriched with glycerol for superior flexibility and penetration through biological membranes.

Nano-scale vesicles maximize surface area for cellular interaction.

3

Chitosan Stabilization

Biocompatible chitosan coating provides positive charge, promoting adhesion to negatively-charged cell membranes and protecting bioactive payload during gastrointestinal transit.

Charge-based adhesion is the key to enhanced absorption.

4

Tangential Flow Filtration (TFF)

Pharmaceutical-grade quality control ensures optimal encapsulation efficiency and consistent results at production scale.

Every batch meets pharmaceutical-grade encapsulation standards.

Glycerosome vs Standard Extraction

Side-by-side comparison of Mushroom Empire's Glycerosome technology versus conventional mushroom extraction methods.

MetricStandard ExtractionME-Glycerosorb™
BioavailabilityBaseline (1x)5-10x Enhanced
GI Tract ProtectionMinimalChitosan-stabilized coating
Cell Membrane AdhesionPassive diffusionActive charge-based adhesion
Compound SpectrumPartial (single-solvent)Full (dual-solvent)
Quality ControlBasic testingPharmaceutical-grade TFF
ConsistencyBatch variationStandardized encapsulation

Partner With Glycerosome Technology

Integrate Mushroom Empire's proprietary Glycerosome extraction into your product line. Available as ME-Glycerosorb™ for B2B partners across Europe.

Glycerosome Extraction Technology | 5-10x Bioavailability | Mushroom Empire | Mushroom Empire